The drive from Cashiers to Phoenix covers approximately 2100 miles. You will travel through Tennessee, Arkansas, Oklahoma, Texas, and New Mexico before entering Arizona. The most direct route involves taking I-40 West to I-17 South. The journey takes about 32 hours of driving time. This route takes you to the desert Southwest.
Total Distance: 3380 km driving distance, 2800 km straight-line air distance.
Plan for multiple overnight stops.
October to April for pleasant weather.