Traveling from Chadds Ford to Buffalo involves crossing the heart of Pennsylvania via I-80 West. This 380-mile journey takes approximately 6 hours of driving time. You will transition onto I-90 West near Erie, Pennsylvania, to reach the Buffalo metropolitan area. The route is characterized by rolling hills and significant elevation changes through the Allegheny National Forest region. It is a popular route for those heading to Niagara Falls or the Great Lakes.
Total Distance: 611 km driving distance; 450 km straight-line air distance.
The I-80 stretch is remote; ensure your fuel tank is at least half full.
June through August for pleasant weather near Lake Erie.