No direct train service exists from Cheyenne to Minneapolis.

How long is the drive?

Approximately 14 hours of driving time.

What is the best route?

I-80 East to I-90 East is the most direct and efficient route.

Yes, there are tolls on some sections of the highway in the Midwest.

Is Minneapolis worth visiting?

Yes, it is a city with a rich cultural history and a vibrant lakefront.

Cheyenne

Minneapolis

Flight Driving

Cheyenne to Minneapolis

Updated: 28 May 2026

The journey from Cheyenne to Minneapolis covers approximately 1,350 kilometers. The most direct driving route involves taking I-80 East to I-90 East, passing through Nebraska and South Dakota. This is a long-distance journey that requires careful planning. Alternatively, you can fly from Cheyenne Regional Airport with connections in hubs like Denver.

Total Distance: 1,350 km driving distance; 1,100 km straight-line air distance.

Fastest Way

Flying is the fastest way to reach Minneapolis, saving over 8 hours.

Cheapest Way

Driving is the most economical choice for families or groups.

Compare Cheyenne to Minneapolis Routes

	Flight Connecting	Driving Direct
Duration	6 hours	14 hours
Avg Price	$400-$700	$180-$250 in fuel
Operator	United Airlines	Personal Vehicle
Route	Cheyenne (CYS) to Minneapolis (MSP).	I-80 E to I-90 E through Sioux Falls.
Tip	Connections are typically through Denver (DEN).	Plan for an overnight stop in Sioux Falls.

Travel Tips

Overnight Stops
Book hotels in advance in cities like Sioux Falls to ensure availability.
Traffic
Avoid driving through Minneapolis during rush hour, as it can add significant time to your trip.
Road Construction
Check for construction updates on I-90, as it is a major corridor.
Snacks
Pack plenty of water and healthy snacks for the long drive.
Vehicle Prep
Get an oil change and tire check before starting this 1,350 km journey.

Safety Tips

Driver Fatigue
Do not attempt to drive the full 14 hours in one day; prioritize rest.
Weather Awareness
If traveling in winter, be prepared for severe snow and ice in the Midwest.
Emergency Kit
Carry a basic emergency kit, including a flashlight and first-aid supplies.
Communication
Keep your phone charged and have a backup power bank.