The journey from Cheyenne to San Francisco is approximately 1,200 miles. Flying from Cheyenne Regional Airport with a connection is the most efficient method, taking about 6 hours. Driving is a multi-day cross-country trip that is not recommended for most travelers. Air travel is the standard and most efficient way to reach the West Coast.
Total Distance: 1,950 km driving distance; 1,600 km straight-line air distance.
Book early to secure reasonable fares.
Spring or autumn for the best weather in San Francisco.