Chicago
Chicago
Des Moines
Des Moines
Bus Driving

Chicago to Des Moines

Updated: 28 May 2026

The journey from Chicago to Des Moines spans about 550 kilometers through the Midwest. Driving via I-88 W and I-80 W is the most direct and practical option, taking about 5.5 hours. Bus travel is also an option, with companies like Jefferson Lines providing service. This route takes you through the heart of the Iowa cornfields.

Total Distance: Driving distance is 550 km; straight-line air distance is 480 km.
Fastest Way
Driving is the fastest method, taking about 5.5 hours.
Cheapest Way
Bus travel is generally the most cost-effective option.
Compare Chicago to Des Moines Routes
Bus
Direct
Driving
Direct
Duration 7 hours 5 hours 30 mins
Avg Price $50-$90 $60-$90 in fuel
Operator Jefferson Lines Personal Vehicle
Route Chicago Union Station to Des Moines I-88 W to I-80 W
Tip Buses are a reliable and affordable way to travel. Expect traffic leaving Chicago; plan your departure accordingly.
Travel Tips
  • Traffic
    Traffic can be heavy leaving Chicago; check GPS for the best route.
  • Weather
    Iowa winters can be snowy; check road conditions before driving.
  • Transport
    A car is recommended for exploring the city and surrounding areas.
  • Safety
    Stay in well-lit, tourist-friendly areas at night.
  • Booking
    Book bus tickets in advance for the best rates.
Safety Tips
  • Driving
    I-80 can be busy; stay alert and follow traffic laws.
  • Winter
    Be prepared for snow and ice in the winter months.
  • Emergency
    Keep your phone charged and have a backup power bank.
  • Walking
    Stay aware of your surroundings in downtown areas.
People Also Ask
  • Is it better to drive or take the bus?
    Driving is very practical for this distance.
  • How long is the drive?
    The drive takes about 5.5 hours.
  • Is Des Moines safe?
    Yes, it is generally safe for tourists in popular areas.
  • What is the best time to visit?
    Summer and fall are best.
  • Are there direct buses?
    Yes, Jefferson Lines offers direct service.
Quick Info
  • From Chicago, Illinois, United States
  • To Des Moines, Iowa, United States
  • Modes
Best Time to Travel

Summer for the Iowa State Fair or fall for the beautiful foliage.

Things to Do in Des Moines
1
Iowa State Capitol
A stunning building with a gold-leaf dome; it is the center of the city.
2
Des Moines Art Center
A beautiful museum with a diverse collection of art.
3
Greater Des Moines Botanical Garden
A beautiful garden with a geodesic dome; it is a must-visit.
4
East Village
A trendy neighborhood with great shops and restaurants.
Tags
Chicago to Des Moines drive bus from Chicago to Des Moines I-88 to I-80 to Des Moines Chicago to Des Moines travel time best way to Des Moines Midwest to Iowa travel Des Moines trip planning