The drive from Cordova to Louisville is a 380-mile trip along I-40 and I-65 North. It takes about 6 hours of driving time. You will travel through Tennessee and into Kentucky. This is a popular route for those traveling between Tennessee and Kentucky. Be prepared for heavy traffic as you enter the Louisville metropolitan area.
Total Distance: 611 km driving distance; 550 km straight-line air distance.
The drive is very straightforward; just follow the signs for I-40 and I-65 North.
Spring and fall, when the weather is mild and pleasant.