Is there a direct flight?

No, all flights from SFO require a connection.

How long is the drive?

Approximately 26 hours of driving time.

What is the best way to get around?

A rental car is the most practical option.

Yes, it is generally safe with standard precautions.

No, there is no direct passenger rail service to Des Moines.

Daly City

Des Moines

Flight Driving

Daly City to Des Moines

Updated: 28 May 2026

Des Moines is a city reachable from Daly City by air. You will fly from San Francisco International Airport to Des Moines International Airport. Driving is a long-distance journey of over 2,700 kilometers, typically following I-80 East.

Total Distance: 2,700 km driving, 2,300 km air distance.

Fastest Way

Flight with one connection.

Cheapest Way

Flight booked in advance.

Compare Daly City to Des Moines Routes

	Flight Connecting	Driving Direct
Duration	5 hours	26 hours
Avg Price	$300 - $600	$450 - $750 in fuel
Operator	United Airlines	Personal Vehicle
Route	SFO to DSM	I-80 E
Tip	Most flights connect through major hubs like Denver or Chicago.	Plan for stops in cities like Salt Lake City or Omaha.

Travel Tips

Airport Transit
The DART bus connects DSM to downtown Des Moines.
Local Travel
Des Moines is a car-centric city; renting a vehicle is recommended.
Dining
Try the local Midwestern cuisine.
Weather
Winters are very cold; pack accordingly.
Packing
Bring comfortable shoes for walking.