No, there is no direct passenger rail service.

What is the best highway?

I-94 West is the primary route.

There is no direct intercity bus service.

De Pere

Minneapolis

Driving

De Pere to Minneapolis

Updated: 31 May 2026

The drive from De Pere to Minneapolis is approximately 280 miles west along I-94. This journey typically takes 4.5 to 5 hours, passing through the scenic landscapes of central and western Wisconsin. Minneapolis, part of the Twin Cities, is known for its vibrant arts scene, numerous lakes, and the Mall of America. It is a major destination for travelers in the Upper Midwest.

Total Distance: 450 km driving distance; 400 km straight-line air distance.

Fastest Way

Driving via I-94 is the fastest, taking about 4.5 hours.

Cheapest Way

Driving your own vehicle is the most practical and cost-effective method.

Compare De Pere to Minneapolis Routes

Driving

Direct

Duration

4.5 hours

Avg Price

$50 - $75 in fuel

Operator

Personal Vehicle

Route

I-41 N to WI-29 W to I-94 W.

I-94 is the most direct route; watch for construction in the Twin Cities.

Travel Tips

Traffic
Minneapolis traffic can be heavy during rush hours; plan accordingly.
Parking
Use parking apps to find affordable parking in downtown Minneapolis.
Navigation
Use a GPS to navigate the city's complex street grid.
Public Transit
Use the METRO light rail system to get around the city efficiently.
Events
Check the Minneapolis event calendar for major concerts and festivals.