The journey from Duluth to Knoxville is a short 300-kilometer drive. Driving via I-75 North and I-40 East is the most practical method, taking about 3 hours. You will pass through the scenic mountains of North Georgia and East Tennessee. This is a popular route for weekend getaways.
Total Distance: 300 km driving, 250 km air distance.
The drive through the mountains is beautiful but watch for fog.
October for the fall foliage in the nearby mountains.