Is there a train to St. Louis?

No, there is no passenger rail service to St. Louis from Duluth.

No, there are no toll roads on this route.

Is St. Louis a good city to visit?

Yes, it has a great downtown and many cultural attractions.

Duluth

St. Louis

Driving

Duluth to St. Louis

Updated: 28 May 2026

The drive from Duluth to St. Louis covers about 700 miles, primarily using I-35 South and I-70 East. This route takes you through the heart of the Midwest. The journey typically takes around 11 hours by car. St. Louis is famous for the Gateway Arch and its vibrant cultural scene. Driving is the most practical mode of transport for this trip.

Total Distance: 1125 km driving distance; 950 km straight-line air distance.

Fastest Way

Driving is the only direct method, taking about 11 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach St. Louis.

Compare Duluth to St. Louis Routes

Driving

Direct

Duration

11 hours

Avg Price

$130-$180 in fuel

Operator

Personal Vehicle

Route

I-35 South to I-70 East.

The route is well-marked and easy to follow.

Travel Tips

Route Planning
I-70 is a major highway; expect some traffic near St. Louis.
Fueling
There are plenty of gas stations along the route, so you won't have trouble finding fuel.
Weather
Check for severe weather alerts in the Midwest, especially during the spring and summer.
Navigation
Use GPS to navigate through the city center to your destination.
Dining
Try the famous St. Louis-style pizza and toasted ravioli.

Safety Tips

Driving Fatigue
Take breaks every 3 hours to stay alert on the long drive.
Winter Driving
Midwest roads can be icy; ensure your car is prepared for winter conditions.
Vehicle Check
Check your tire pressure and fluid levels before starting this long trip.
Emergency
Keep a basic emergency kit in your car at all times.