The drive from Fort Scott to San Antonio is approximately 700 miles. You will travel south on US-69 and then transition to I-35. The journey takes about 11 hours of driving time. This is a direct and simple route across the plains.
Total Distance: Driving distance 1,150 km; Air distance 1,000 km.
I-35 is a well-maintained highway with many stops.
March to May or October to November for mild weather.