Is I-35 the best route?

Yes, I-35 is the most direct and well-maintained highway.

How long is the flight?

Flights typically take 5 to 7 hours with a layover.

Are there direct flights?

Direct flights are rare; most require a connection.

What is the best time to leave?

Leaving early in the morning helps avoid traffic in major cities.

Is Des Moines walkable?

Downtown Des Moines is very walkable and features a skywalk system.

Gainesville

Des Moines

Flight Driving

Gainesville to Des Moines

Updated: 31 May 2026

Traveling from Gainesville to Des Moines covers roughly 850 miles, primarily following the I-35 corridor. This route takes you through Oklahoma, Kansas, and Missouri before entering Iowa. The drive is straightforward but long, requiring about 13 hours of pure driving time. Alternatively, you can fly from DFW to Des Moines International Airport (DSM). The landscape changes from Texas scrubland to the expansive cornfields of the Midwest.

Total Distance: 1,360 km driving distance; 1,180 km straight-line air distance.

Fastest Way

Flying from DFW is the fastest, taking roughly 5 hours.

Cheapest Way

Driving is the most economical choice for solo travelers or families.

Compare Gainesville to Des Moines Routes

	Flight Connecting	Driving Direct
Duration	5 hours including layover	13 hours
Avg Price	$300-$500	$140-$200 in fuel
Operator	United Airlines	Personal Vehicle
Route	DFW to DSM via hub airports.	I-35 N through Oklahoma City, Wichita, and Kansas City.
Tip	Check flights from Love Field (DAL) for potential budget options.	Stop in Kansas City for a meal to break up the long drive.

Travel Tips

Toll Roads
Have a toll tag ready for the Kansas Turnpike to save time.
Hydration
Keep plenty of water in the car, especially during summer months.
Hotel Booking
Book hotels in advance if traveling during major events in Kansas City.
Cruise Control
Use cruise control on flat stretches of I-35 to improve fuel efficiency.
Vehicle Check
Check your oil and coolant levels before departing on this long haul.