Flight
Driving
Greenville to Minneapolis
Updated: 28 May 2026
The route from Greenville to Minneapolis takes you north through the heart of the Mississippi River Valley. Driving involves taking US-61 North, often called the Great River Road, through Memphis and St. Louis before reaching Minnesota. Flying requires a connection, usually through a major hub like Chicago or Memphis. Minneapolis is significantly colder than Greenville, so pack accordingly. This journey covers approximately 950 miles.
Total Distance: 1,530 km driving, 1,250 km air distance.
Fastest Way
Flying from Jackson-Medgar Wiley Evers International Airport is the fastest.
Cheapest Way
Driving is the most budget-friendly option for this route.
Compare Greenville to Minneapolis Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 5 hours 30 mins | 15 hours |
| Avg Price | $400-$750 | $250-$400 in fuel |
| Operator | Delta Air Lines | Personal Vehicle |
| Route | JAN to MSP. | US-61 N to I-55 N, then I-35 N. |
| Tip | Delta offers the most frequent service to Minneapolis from the region. | The Great River Road offers scenic views but adds time to your trip. |
Travel Tips
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Winter DrivingIf driving in winter, ensure your vehicle has snow tires and an ice scraper.
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Airport TransportThe METRO Blue Line light rail connects the airport directly to downtown Minneapolis.
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LayeringMinneapolis weather changes rapidly; always dress in layers.
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River RoadTake your time on the Great River Road; it is a designated National Scenic Byway.
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DiningTry the local 'Juicy Lucy' burger at a neighborhood pub.
Safety Tips
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Black IceBe extremely cautious of black ice on bridges and overpasses during the colder months.
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Emergency SuppliesKeep a blanket and extra warm clothing in your car during winter travel.
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NavigationUse GPS to navigate the complex highway interchanges in St. Louis and Chicago.
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WildlifeBe alert for deer crossing the road, especially at dawn and dusk in rural areas.
People Also Ask
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How long is the flight?Total travel time including layovers is usually 5 to 7 hours.
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Is there a train?No, there is no direct passenger rail service from Greenville to Minneapolis.
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What is the best route by car?I-55 North to I-35 North is the most direct interstate route.
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Is Minneapolis safe?Like any major city, it has safe areas and areas to avoid; stay aware of your surroundings.
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Do I need a passport?No, this is a domestic trip within the United States.
Quick Info
- From Greenville, Mississippi, United States
- To Minneapolis, Minnesota, United States
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Modes
Best Time to Travel
Summer for the best weather, or autumn for the fall foliage along the river.
Things to Do in Minneapolis
1
Mall of America
Located in Bloomington, this is the largest mall in the US. It features an indoor theme park and aquarium.
2
Minneapolis Institute of Art
A massive museum with over 90,000 works of art. Admission is free for the general public.
3
Chain of Lakes
A series of interconnected lakes in Minneapolis perfect for kayaking, biking, and walking.
4
Minnehaha Falls
A stunning 53-foot waterfall located within a city park. It is beautiful in both summer and winter.
Tags
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