The drive from Greenville to Shreveport covers about 280 miles and takes roughly 4.5 hours. You will travel west through Mississippi, Arkansas, and Louisiana on US-82 and I-20. The route takes you through diverse landscapes, from the Mississippi Delta to the piney woods of Louisiana. It is a long-distance drive that requires careful planning and vehicle preparation. Ensure you have plenty of fuel and snacks for this multi-state journey.
Total Distance: 450 km driving distance, 390 km straight-line air distance.
Stop in Monroe for a break.
Spring or autumn to avoid the intense heat and humidity of the Louisiana summer.