Hattiesburg
Hattiesburg
Huntsville
Huntsville
Driving

Hattiesburg to Huntsville

Updated: 28 May 2026

The drive from Hattiesburg to Huntsville takes about 5 hours and covers 450 kilometers. You will travel north on I-59 to Birmingham, then north on I-65 into Huntsville. This route takes you through the heart of Mississippi and Alabama. It is a straightforward drive on major interstate highways. Huntsville is known for its space history, museums, and cultural attractions.

Total Distance: 450 km driving distance; 400 km straight-line air distance.
Fastest Way
Driving is the fastest method, taking 5 hours.
Cheapest Way
Driving your own vehicle is the most practical and cheapest way to travel.
Compare Hattiesburg to Huntsville Routes
Driving
Direct
Duration
5 hours
Avg Price
$60-$80 in fuel
Operator
Personal Vehicle
Route
I-59 N to I-65 N.

Traffic in Birmingham and Huntsville can be heavy; plan accordingly.

Travel Tips
  • Route Choice
    I-65 is a major interstate; expect heavy truck traffic.
  • Dining
    Huntsville has a variety of local restaurants serving Southern cuisine.
  • Planning
    Check for local events before you travel.
  • Navigation
    Use a GPS to navigate the highway transitions.
  • Parking
    Parking is generally easy to find in Huntsville.
Safety Tips
  • Speed Limits
    Be aware of speed limit changes on I-65.
  • Weather
    Check for heavy rain alerts during the summer.
  • Fatigue
    Take breaks to stay alert on the highway.
  • Emergency
    Keep a basic emergency kit in your car.
People Also Ask
  • Is there a train?
    There is no passenger train service to Huntsville.
  • How long is the drive?
    The drive takes approximately 5 hours.
  • What is the best route?
    I-59 to I-65 is the most efficient route.
  • Are there tolls?
    There are no tolls on this route.
  • Is it a safe drive?
    Yes, it is a major interstate route.
Quick Info
  • From Hattiesburg, Mississippi, United States
  • To Huntsville, Alabama, United States
  • Modes
Best Time to Travel

Spring and Autumn are best for outdoor activities in Huntsville.

Things to Do in Huntsville
1
U.S. Space & Rocket Center
A world-class museum featuring space exploration exhibits and rockets.
2
Huntsville Botanical Garden
A beautiful garden with seasonal displays and walking trails.
3
Monte Sano State Park
Offers hiking, camping, and scenic views of the city.
4
Downtown Huntsville
Features local shops, restaurants, and cultural attractions.
Tags
Hattiesburg to Huntsville drive I-59 to I-65 travel Hattiesburg to Huntsville Huntsville travel driving time Hattiesburg to Huntsville road trip how to get to Huntsville Huntsville tourism