Driving
Hattiesburg to Biloxi
Updated: 28 May 2026
The trip from Hattiesburg to the coastal city of Biloxi spans roughly 75 miles. You will primarily travel south on US-49, which connects the Pine Belt directly to the Gulf Coast. This route takes you through the De Soto National Forest, offering scenic pine views. The drive is efficient and typically takes about one hour and fifteen minutes. Upon reaching the coast, you will merge onto I-10 East to reach the heart of Biloxi.
Total Distance: 120 km driving distance; 115 km straight-line air distance.
Fastest Way
Driving via US-49 South is the fastest route, taking 75 minutes.
Cheapest Way
Driving your own car is the most cost-effective way to reach Biloxi.
Compare Hattiesburg to Biloxi Routes
Driving
Direct
Duration
1 hour 15 mins
Avg Price
15 USD
Operator
Personal Vehicle
Route
US-49 South to I-10 East.
The transition from US-49 to I-10 can be busy; stay alert for merging traffic.
Travel Tips
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Sun ProtectionThe coastal sun is intense; bring sunscreen and sunglasses.
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TrafficHighway 90 can get congested on weekends; plan your arrival accordingly.
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DiningTry the local fresh seafood at restaurants along the Back Bay.
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ParkingMost casinos offer free parking garages for visitors.
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EventsCheck the local calendar for festivals like Cruisin' The Coast to avoid traffic spikes.
Safety Tips
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Hurricane AwarenessAlways check weather reports for tropical activity before traveling to the coast.
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Water SafetyFollow all posted warnings regarding swimming conditions at the beach.
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DrivingBe mindful of heavy tourist traffic on Highway 90.
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EmergencyKeep your vehicle's emergency kit stocked with water and supplies.
People Also Ask
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Is there a bus to Biloxi?There is no direct public bus service from Hattiesburg to Biloxi.
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How long is the drive?The drive takes approximately 75 minutes.
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Are there tolls?No, there are no toll roads on this route.
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Is US-49 safe?Yes, it is a major highway connecting the interior to the coast.
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What is the best time to visit?Spring and fall offer the most comfortable weather.
Quick Info
- From Hattiesburg, Mississippi, United States
- To Biloxi, Mississippi, United States
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Modes
Best Time to Travel
Late spring or early autumn to avoid the peak humidity and hurricane season.
Things to Do in Biloxi
1
Biloxi Lighthouse
Visit this historic landmark standing in the middle of Highway 90. It is a symbol of the city's resilience.
2
Beau Rivage Resort
Experience luxury gaming and dining at this premier coastal resort. It offers views of the Gulf of Mexico.
3
Maritime and Seafood Industry Museum
Learn about the rich history of the Gulf Coast fishing industry. The museum features interactive exhibits.
4
Biloxi Beach
Relax on the sandy shores of the Mississippi Sound. It is perfect for a day of sun and swimming.
Tags
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Mississippi Gulf Coast travel
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