The drive from Iowa, Louisiana to Biloxi, Mississippi covers 260 miles, primarily using I-10 East. You will pass through Baton Rouge and New Orleans. The trip typically takes four hours. This route is a popular path for travelers heading to the Mississippi Gulf Coast.
Total Distance: 418 km driving, 380 km air distance.
Expect heavy traffic in Baton Rouge and New Orleans.
Spring or Fall for pleasant weather in Biloxi.