The drive from Hattiesburg to Monroe takes about 4 hours and covers 350 kilometers. You will travel north on US-49 to Jackson, then west on I-20 into Monroe. This route takes you through the heart of Mississippi and into North Louisiana. It is a straightforward drive on major interstate highways. Monroe is known for its riverfront, museums, and cultural attractions.
Total Distance: 350 km driving distance; 310 km straight-line air distance.
Traffic in Jackson and Monroe can be heavy; plan accordingly.
Spring and Autumn are best for outdoor activities in Monroe.