The trip from Hilton Head Island to Raleigh spans approximately 320 miles. The most common route involves taking I-95 North to I-40 West. This journey typically takes about 5 hours of driving time. You will travel through the heart of South Carolina and into the Research Triangle of North Carolina. The route is mostly flat and passes through several historic towns. It is a popular route for those moving between the coast and the capital.
Total Distance: 515 km driving distance; 450 km straight-line air distance.
I-95 North through South Carolina has several construction zones; stay alert.
Spring and autumn provide the most comfortable driving weather.