How long is the drive?

The drive takes about 7.5 hours.

Amtrak serves St. Louis, but there is no direct train from Detroit.

What is the best route?

I-75 South to I-70 West is the most direct path.

The city has safe areas; stay in tourist-focused zones.

No, this route is generally toll-free.

Huntington Woods

St. Louis

Driving

Huntington Woods to St. Louis

Updated: 30 May 2026

The drive from Huntington Woods to St. Louis covers approximately 500 miles, taking you through Ohio, Indiana, and Illinois before reaching Missouri. The most efficient route is I-75 South to I-70 West. The trip typically takes 7.5 hours of driving time. This route is a major artery for travelers heading to the Gateway Arch or the vibrant neighborhoods of St. Louis.

Total Distance: 805 km driving distance, 650 km straight-line air distance.

Fastest Way

Driving via I-75 and I-70 is the fastest method, taking 7.5 hours.

Cheapest Way

Driving is the most cost-effective way to reach St. Louis.

Compare Huntington Woods to St. Louis Routes

Driving

Direct

Duration

7 hours 30 mins

Avg Price

$80-$110 in fuel

Operator

Personal Vehicle

Route

I-75 South to I-70 West.

I-70 through Indianapolis can be busy; check traffic before you leave.

Travel Tips

Traffic Planning
Avoid the Indianapolis and St. Louis rush hours to save time.
Rest Stops
There are many service plazas along I-70 in Indiana and Illinois.
Parking
Use parking apps to find affordable spots near the Gateway Arch.
Dining
Try the famous St. Louis-style pizza and toasted ravioli.
Navigation
Use Waze to avoid construction delays on I-70.

Safety Tips

Highway Vigilance
Stay alert on the long stretches of I-70; it is a major trucking route.
City Safety
Stick to well-lit, tourist-friendly areas in downtown St. Louis.
Vehicle Prep
Check your oil and tires before this long drive.
Emergency Kit
Carry a basic emergency kit with water and snacks.