The drive from Hyannis to Manchester, New Hampshire, covers 200 kilometers. You will head north on Route 6, then take I-495 to I-93 North, passing through the Boston suburbs. The trip takes about two and a half hours, depending on traffic. It is a straightforward route into the Granite State. Manchester is the largest city in New Hampshire and a major regional hub.
Total Distance: 200 km driving, 170 km air distance.
Avoid Boston rush hour to ensure a smooth trip.
Autumn for the beautiful fall foliage throughout New Hampshire.