The drive from Isle of Palms to Nashville is an 850-kilometer journey west. You will follow I-26 West and then I-40 West, taking approximately 8.5 to 9 hours. Nashville is the capital of Tennessee and is famous for its music scene, particularly country music. The route takes you through the Carolinas and into Tennessee. It is a long drive that requires careful planning.
Total Distance: 850 km driving distance; 720 km straight-line air distance.
Expect heavy traffic in the Nashville metro area.
Spring and fall for pleasant weather and outdoor activities.