The drive from Jefferson to Las Vegas is approximately 3,200 kilometers. You will head north to I-40 and follow it west through Tennessee, Arkansas, Oklahoma, Texas, New Mexico, and Arizona into Nevada. This journey takes about 32 hours of driving time. It is a major cross-country trip that requires multiple days.
Total Distance: 3,200 km driving distance; 2,800 km straight-line air distance.
This is a multi-day trip; plan for overnight stops.
March to May or September to November for mild weather.