Driving
Jefferson to Saint Louis
Updated: 31 May 2026
The drive from Jefferson to St. Louis is approximately 900 kilometers. You will head north on I-85 to Atlanta, then take I-75 to I-24 West through Nashville, and finally I-64 West into St. Louis. This journey takes about 10 hours. You will pass through the scenic landscapes of Tennessee and Illinois.
Total Distance: 900 km driving distance; 800 km straight-line air distance.
Fastest Way
Driving is the fastest, as there are no direct flights from local regional airports.
Cheapest Way
Driving is the most cost-effective way to reach St. Louis.
Compare Jefferson to Saint Louis Routes
Driving
Direct
Duration
10 hours
Avg Price
$140-$200 in fuel
Operator
Personal Vehicle
Route
I-85 N to I-75 N to I-24 W to I-64 W
Nashville traffic can be heavy; plan your timing carefully.
Travel Tips
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TrafficThe I-270 loop around St. Louis can be busy.
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WalkingThe downtown area is walkable, but a car is helpful for other areas.
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WeatherSummers are hot and humid; winters can be cold.
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DiningTry the local toasted ravioli and gooey butter cake.
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ParkingUse the many parking garages available downtown.
Safety Tips
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Road SafetyBe cautious of heavy traffic in Nashville and St. Louis.
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ParkingLock your car and keep valuables out of sight.
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AwarenessStay in well-lit areas at night.
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EmergencyKeep a roadside assistance contact handy.
People Also Ask
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How long is the drive?The drive takes about 10 hours.
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Is it a scenic drive?Yes, the Tennessee landscape is beautiful.
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Are there tolls?Some roads in Illinois may have tolls.
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What is the best time to visit?Spring and early autumn are best.
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Can I take a train?There is no direct train service from Jefferson to St. Louis.
Quick Info
- From Jefferson, Georgia, United States
- To Saint Louis, Missouri, United States
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Modes
Best Time to Travel
May to June or September to October for mild weather.
Things to Do in Saint Louis
1
Gateway Arch
Visit the iconic monument and take a tram to the top.
2
Forest Park
Explore the massive park featuring a zoo, art museum, and science center.
3
City Museum
Experience this unique, interactive playground for all ages.
4
Anheuser-Busch Brewery
Take a tour of the historic brewery and see the Clydesdales.
Tags
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