The journey from Johns Island to Myrtle Beach spans approximately 160 miles along the South Carolina coast. Most travelers utilize US-17 North, which offers a scenic route through the Lowcountry. The drive typically takes 3 hours depending on traffic near Charleston and Georgetown. You will pass through historic towns and marshland landscapes. This route is primarily served by private vehicle as there is no direct rail connection.
Total Distance: 257 km driving distance, 225 km straight-line air distance.
Avoid rush hour traffic in downtown Charleston by taking I-526 to bypass the city center.
April to May for mild temperatures and fewer crowds before the peak summer season.