St. Louis
St. Louis
Myrtle Beach
Myrtle Beach
Flight Driving

St. Louis to Myrtle Beach

Updated: 28 May 2026

The journey from St. Louis to Myrtle Beach is approximately 1,300 km. Driving via I-64 and I-74 takes about 13 hours. Flying into Myrtle Beach International Airport (MYR) is a popular choice, usually requiring a connection. Myrtle Beach is a famous coastal destination known for its beaches, golf courses, and family-friendly attractions.

Total Distance: 1,300 km driving distance; 1,100 km straight-line air distance.
Fastest Way
Flying is significantly faster.
Cheapest Way
Driving is often cheaper than flying.
Compare St. Louis to Myrtle Beach Routes
Flight
Connecting
Driving
Direct
Duration 4 hours 13 hours
Avg Price $250 - $500 $180 in fuel
Operator American Airlines Personal Vehicle
Route STL to MYR via CLT or ATL. I-64 E to I-77 S to I-74 E.
Tip MYR is a very convenient airport for the beach. This is a long drive; plan for an overnight stop.
Travel Tips
  • Airport
    MYR is easy to navigate.
  • Transport
    Renting a car is recommended for exploring the area.
  • Weather
    Summers are hot and humid; plan accordingly.
  • Sun Protection
    The South Carolina sun is strong; wear sunscreen.
  • Events
    Check the city calendar for festivals and events.
Safety Tips
  • Traffic
    Traffic can be heavy during peak season; plan for delays.
  • Emergency
    Keep your phone charged for navigation.
  • Hydration
    Drink plenty of water in the South Carolina heat.
  • Night Driving
    Be alert for tourists who may be unfamiliar with the roads.
People Also Ask
  • Is it better to fly or drive?
    Flying is usually faster and more cost-effective.
  • How long is the flight?
    Total travel time including layovers is usually 4 hours.
  • Are there direct flights?
    No, you will likely connect through a hub like Charlotte or Atlanta.
  • What is the best way to get around?
    A rental car is the most convenient option.
  • Is Myrtle Beach safe?
    Yes, the tourist areas are generally very safe.
Quick Info
  • From St. Louis, Missouri, United States
  • To Myrtle Beach, South Carolina, United States
  • Modes
Best Time to Travel

Spring and Fall for pleasant weather.

Things to Do in Myrtle Beach
1
Myrtle Beach Boardwalk
A popular boardwalk with shops, restaurants, and rides.
2
Broadway at the Beach
A large entertainment complex with shops and attractions.
3
Myrtle Beach State Park
A beautiful park with beach access and trails.
4
Ripley's Aquarium
A popular aquarium with a variety of marine life.
Tags
St. Louis to Myrtle Beach STL to MYR flights driving to Myrtle Beach I-64 route South Carolina travel Myrtle Beach transport St. Louis travel best way to Myrtle Beach