The drive from Johnson City to Orlando covers approximately 650 miles. You will take I-26 East to I-95 South, then I-4 East into Orlando. The trip takes about 10 hours of driving time. This is a long-distance route that takes you from the mountains of Tennessee to the heart of Florida. It is a popular route for families heading to the theme parks.
Total Distance: 1046 km driving distance and 850 km straight-line air distance.
Plan for an overnight stop if you want to avoid a very long day of driving.
Spring or fall for pleasant temperatures and fewer crowds.