Knoxville
Knoxville
Minneapolis
Minneapolis
Flight Driving

Knoxville to Minneapolis

Updated: 01 Jun 2026

The route from Knoxville to Minneapolis takes you through the heart of the Midwest. By car, you will cover approximately 1,600 kilometers, typically routing through Louisville, Chicago, and Madison. This drive takes about 16 to 18 hours of road time. Flying from McGhee Tyson Airport (TYS) to Minneapolis-St. Paul International Airport (MSP) is a convenient alternative, often involving a connection in a hub like Chicago or Detroit. Minneapolis is famous for its chain of lakes and the Mall of America. Be prepared for significant temperature drops if traveling during the winter months.

Total Distance: Driving distance 1,620 km, straight-line air distance 1,350 km.
Fastest Way
Flying is the fastest, with a total travel time of about 5 hours.
Cheapest Way
Driving is the most cost-effective for multiple travelers.
Compare Knoxville to Minneapolis Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 17 hours
Avg Price $250 - $500 $200 - $300 in fuel
Operator Delta Air Lines Personal Vehicle
Route TYS to MSP via DTW or ORD. I-65 N to I-90 W through Chicago.
Tip Book early to avoid high prices on this popular route. Avoid Chicago traffic by taking the I-294 bypass.
Travel Tips
  • Winter Travel
    If driving in winter, ensure your car has an emergency kit and snow tires.
  • Skyway System
    Minneapolis has an extensive indoor skyway system to navigate downtown in winter.
  • Public Transit
    The METRO light rail connects the airport to downtown and the Mall of America.
  • Dining
    Try a Jucy Lucy burger, a local specialty with cheese inside the patty.
  • Navigation
    Use a GPS to navigate the complex highway interchanges around Chicago.
Safety Tips
  • Road Safety
    Be cautious of high-speed traffic on I-90 through Wisconsin.
  • Weather Alerts
    Check weather forecasts frequently during the winter months.
  • Personal Safety
    Stay aware of your surroundings in busy transit hubs.
  • Vehicle Prep
    Check your battery and coolant levels before a long-distance drive.
People Also Ask
  • Is Minneapolis cold?
    Yes, winters are very cold with significant snowfall.
  • How long is the drive?
    Expect 16 to 18 hours of driving time.
  • Are there direct flights?
    Direct flights are rare; most involve a connection.
  • What is the best way to get around?
    Light rail and ride-shares are excellent for tourists.
  • Is the Mall of America worth it?
    Yes, it is a unique shopping and entertainment destination.
Quick Info
  • From Knoxville, Tennessee, United States
  • To Minneapolis, Minnesota, United States
  • Modes
Best Time to Travel

Summer for lake activities or late spring for blooming parks.

Things to Do in Minneapolis
1
Mall of America
The largest mall in the US, located in Bloomington. It features an indoor theme park and aquarium.
2
Minnehaha Falls
A stunning 53-foot waterfall located within a city park. It is beautiful in all seasons.
3
Chain of Lakes
A series of interconnected lakes perfect for kayaking, biking, and walking. It is a local favorite.
4
Minneapolis Sculpture Garden
Home to the famous Spoonbridge and Cherry sculpture. It is a great spot for photos.
Tags
Knoxville to Minneapolis flights to Minneapolis driving to Minnesota I-65 to I-90 traveling to Twin Cities TYS to MSP road trip Knoxville to Minneapolis best travel options