Flight
Driving
Knoxville to Pittsburgh
Updated: 01 Jun 2026
The drive from Knoxville to Pittsburgh is a scenic journey through the Appalachian Mountains. Covering approximately 650 kilometers, the route primarily follows I-79 North. This drive takes about 7 to 8 hours. Flying from McGhee Tyson Airport (TYS) to Pittsburgh International Airport (PIT) is also an option, though it typically requires a connection. Pittsburgh is known for its three rivers, industrial history, and vibrant cultural districts. Be prepared for winding roads and potential fog in the mountain passes during your drive.
Total Distance: Driving distance 660 km, straight-line air distance 550 km.
Fastest Way
Flying is the fastest, taking about 4 hours total.
Cheapest Way
Driving is the most cost-effective method for this trip.
Compare Knoxville to Pittsburgh Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 4 hours | 7 hours 30 mins |
| Avg Price | $200 - $400 | $90 - $130 in fuel |
| Operator | American Airlines | Personal Vehicle |
| Route | TYS to PIT via CLT or PHL. | I-75 N to I-79 N through West Virginia. |
| Tip | Flights are convenient but require a layover. | The drive through West Virginia is very scenic but hilly. |
Travel Tips
-
NavigationPittsburgh's streets can be confusing; use a reliable GPS.
-
ParkingDowntown parking can be expensive; look for public garages.
-
WeatherBe prepared for sudden rain showers throughout the year.
-
DiningTry a Primanti Bros. sandwich, a local staple with fries inside.
-
AirportPIT is located about 20 minutes from downtown by car.
Safety Tips
-
Mountain DrivingUse lower gears on steep descents in West Virginia.
-
Road ConditionsWatch for deer on rural stretches of I-79.
-
Urban SafetyStay in well-lit areas when walking at night.
-
Emergency PrepKeep a flashlight and blanket in your car for emergencies.
People Also Ask
-
Is Pittsburgh safe?Yes, it is generally safe for visitors in tourist areas.
-
How long is the drive?Expect 7 to 8 hours of driving time.
-
Are there direct flights?No, direct flights are not currently available.
-
What is the best way to get around?A car is helpful, but downtown is walkable.
-
Is the incline worth it?Yes, it is an iconic Pittsburgh experience.
Quick Info
- From Knoxville, Tennessee, United States
- To Pittsburgh, Pennsylvania, United States
-
Modes
Best Time to Travel
Autumn for the stunning fall foliage in the surrounding hills.
Things to Do in Pittsburgh
1
Duquesne Incline
A historic funicular that takes you up Mount Washington for the best view of the city.
2
Carnegie Museum of Natural History
A world-class museum famous for its dinosaur collection.
3
Point State Park
Located at the confluence of the three rivers, it is a beautiful spot for a walk.
4
Strip District
A vibrant neighborhood known for its food markets, shops, and restaurants.
Tags
Knoxville to Pittsburgh
driving to Pittsburgh
flights to Pittsburgh
I-79 route
traveling to Pennsylvania
TYS to PIT
road trip Knoxville to Pittsburgh
best travel options
