The drive from Lake George to Baltimore is approximately 350 miles. You will travel south on I-87 S and then take I-95 S to reach Maryland. The journey takes about 6 hours. This route takes you through the Hudson Valley, around New York City, and through Philadelphia.
Total Distance: 560 km driving distance; 450 km straight-line air distance.
Expect heavy traffic near New York City and Philadelphia.
Spring or autumn for mild weather.