Driving
Lander to Des Moines
Updated: 31 May 2026
The drive from Lander to Des Moines covers approximately 1,300 kilometers. You will head east on WY-220 to I-25, then transition to I-80 East across Nebraska and Iowa. This route takes roughly 13 hours of driving time. You will pass through the vast agricultural landscapes of the Platte River Valley and the rolling hills of Iowa.
Total Distance: 1,300 km driving distance; 1,100 km straight-line air distance.
Fastest Way
Driving is the fastest method, taking 13 hours of active road time.
Cheapest Way
Driving is the most practical and cost-effective way to reach Des Moines.
Compare Lander to Des Moines Routes
Driving
Direct
Duration
13 hours
Avg Price
$180-$240 in fuel
Operator
Personal Vehicle
Route
WY-220 to I-25 S, then I-80 E all the way to Des Moines.
Stop in Omaha, Nebraska, for a mid-trip break.
Travel Tips
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Speed LimitsI-80 in Nebraska and Iowa has high speed limits; stay alert.
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Rest StopsNebraska and Iowa have excellent rest areas along I-80.
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WeatherCheck for severe thunderstorm warnings in the spring.
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Hotel BookingsBook your hotel in Des Moines in advance.
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TrafficAvoid driving through Des Moines during rush hours.
Safety Tips
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FatigueTake regular breaks to stay alert.
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Emergency KitKeep a flashlight, water, and snacks in the car.
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TowingCheck your vehicle's cooling system.
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CommunicationEnsure your phone is charged.
People Also Ask
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Is there a train to Des Moines?No, there is no direct passenger train service to Des Moines.
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How long is the drive?The drive takes about 13 hours.
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Are there tolls?No, there are no tolls on I-80 in Nebraska or Iowa.
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What is the best route?I-80 is the most direct route.
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Is it safe to drive at night?It is generally safe, but be cautious of wildlife.
Quick Info
- From Lander, Wyoming, United States
- To Des Moines, Iowa, United States
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Modes
Best Time to Travel
Late spring or early autumn for comfortable driving weather.
Things to Do in Des Moines
1
Iowa State Capitol
Visit the capitol in Des Moines, known for its beautiful gold-leaf dome.
2
Greater Des Moines Botanical Garden
A beautiful garden in Des Moines with a unique geodesic dome.
3
Des Moines Art Center
A world-class art museum with a diverse collection.
4
East Village
A vibrant area in downtown Des Moines with shops, restaurants, and nightlife.
Tags
Lander to Des Moines drive
driving Lander to Des Moines
I-80 route
Wyoming to Iowa road trip
Des Moines travel guide
Lander to Des Moines distance
best route to Des Moines
driving through Nebraska and Iowa
