The drive from Mankato to Sioux Falls is a quick 2.5-hour journey covering 230 kilometers. You will take MN-60 West, which connects directly to I-90 West near Worthington. This route is very efficient and passes through scenic rural Minnesota and South Dakota landscapes. It is a popular route for weekend getaways. Expect well-maintained roads throughout the entire trip.
Total Distance: 230 km driving distance, 210 km straight-line air distance.
Worthington is a great place to stop for a quick lunch.
Late spring to early autumn for the best driving conditions.