The drive from Monona to Kansas City covers approximately 750 kilometers. You will primarily use I-90 West to I-35 South. Expect a total travel time of about 8 hours. This route takes you through Iowa, passing through Des Moines. It is a major interstate journey that is straightforward and well-serviced.
Total Distance: 750 km driving distance; 650 km straight-line air distance.
I-35 is a very direct route into Kansas City.
Spring or Fall for comfortable temperatures for sightseeing.