Opelika
Opelika
Memphis
Memphis
Flight Driving

Opelika to Memphis

Updated: 28 May 2026

The journey from Opelika to Memphis covers roughly 500 kilometers. You can drive directly via I-85 and I-22, which takes about 5.5 hours. Alternatively, you can drive to Atlanta and fly to Memphis International Airport (MEM). This route takes you through the heart of the Deep South.

Total Distance: 500 km driving distance; 450 km straight-line air distance.
Fastest Way
Flying from Atlanta (ATL) to Memphis (MEM) is the fastest at 3 hours.
Cheapest Way
Driving is the most cost-effective for all group sizes.
Compare Opelika to Memphis Routes
Flight
Direct from ATL
Driving
Direct
Duration 3 hours total 5 hours 30 mins
Avg Price $200-$400 $70-$100 in fuel
Operator Delta Air Lines Personal Vehicle
Route Drive to ATL, fly to MEM. I-85 N to I-22 W.
Tip Flights are quick and convenient from the Atlanta hub. The drive is straightforward and mostly on major interstates.
Travel Tips
  • Traffic
    Avoid I-240 during rush hour in Memphis.
  • Parking
    Use public parking garages downtown for easy access to attractions.
  • Weather
    Memphis can be hot and humid in the summer; stay hydrated.
  • Dining
    Try the famous Memphis-style barbecue at a local restaurant.
  • Safety
    Stay in well-lit areas when walking downtown at night.
Safety Tips
  • Urban Awareness
    Stay in well-lit areas when walking downtown at night.
  • Vehicle Security
    Keep your car locked and valuables out of sight.
  • Road Conditions
    Be cautious of construction zones on I-22.
  • Emergency Prep
    Keep a roadside emergency kit in your vehicle.
People Also Ask
  • Is there a direct train?
    No, there is no direct rail service from Opelika to Memphis.
  • How long is the drive?
    The drive takes about 5.5 hours without major stops.
  • Are there direct flights?
    Yes, Delta offers direct flights from Atlanta to Memphis.
  • What is the best highway?
    I-22 West is the primary highway for this route.
  • Is Memphis safe?
    Downtown and the tourist districts are generally safe.
Quick Info
  • From Opelika, Alabama, United States
  • To Memphis, Tennessee, United States
  • Modes
Best Time to Travel

April to May or September to October for mild weather.

Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley. It is one of the most famous homes in the country.
2
Beale Street
Experience the heart of Memphis blues music. It is full of clubs and restaurants.
3
National Civil Rights Museum
Explore the history of the civil rights movement at the Lorraine Motel.
4
Sun Studio
Tour the studio where rock and roll history was made.
Tags
Opelika to Memphis driving to Tennessee flights to MEM travel from Alabama I-22 route Atlanta to Memphis flights road trip to Memphis Memphis travel guide
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