No, there is no direct bus service between Peoria and Louisville.

How long is the drive?

It takes about 5 hours via I-74 and I-65.

Yes, the highways are well-maintained.

What is the best way to get around?

A car is recommended for flexibility.

No, there is no passenger rail service.

Peoria

Louisville

Driving

Peoria to Louisville

Updated: 31 May 2026

The journey from Peoria to Louisville is a 500 km drive southeast via I-74 and I-65. It typically takes 5 hours by car. There is no direct bus or train service, making driving the most practical option. Louisville is a historic city on the Ohio River, famous for the Kentucky Derby and its bourbon distilleries.

Total Distance: 500 km driving, 450 km air distance.

Fastest Way

Driving is the fastest, taking 5 hours.

Cheapest Way

Driving is the only practical way to travel between these cities.

Compare Peoria to Louisville Routes

Driving

Direct

Duration

5 hours

Avg Price

$60 - $100

Operator

Personal Vehicle

Route

I-74 to I-65 S.

The route is straightforward and well-maintained.

Travel Tips

Transportation
A car is recommended for exploring the city and surrounding areas.
Dining
Explore the local food scene, including the famous Hot Brown sandwich.
Parking
Parking is available in downtown garages.
Weather
Winters can be cold; pack accordingly.
Airport Access
Louisville Muhammad Ali International Airport is 15 minutes from downtown.