The drive from Port Orange to Tallahassee covers roughly 400 kilometers across North Florida. You will typically take I-4 West to I-75 North, then merge onto I-10 West. This route takes you through the heart of the state, passing near Gainesville and Lake City. The journey usually takes about 4 hours and 15 minutes. Tallahassee, the state capital, offers a hilly landscape distinct from the coastal areas.
Total Distance: 400 km driving distance; 360 km straight-line air distance.
Stop in Lake City for a quick break and fuel.
Spring for the blooming azaleas and mild weather.