The drive from Santa Cruz to Palm Springs covers approximately 750 kilometers. You will head south on Highway 1, transition to US-101, and eventually take I-5 and CA-58 to cross the Tehachapi Mountains. This route takes you through the Central Valley and into the Coachella Valley. Expect a travel time of roughly 7 to 8 hours depending on traffic in Los Angeles. The landscape shifts from coastal redwoods to arid desert terrain.
Total Distance: Driving distance 750 km, Air distance 600 km.
Avoid the Grapevine section of I-5 during peak holiday traffic.
October to April to avoid the extreme summer heat of the desert.