Shepherdsville
Shepherdsville
Memphis
Memphis
Driving

Shepherdsville to Memphis

Updated: 31 May 2026

The drive from Shepherdsville to Memphis is approximately 350 miles, primarily using I-65 South and I-40 West. You will travel through Nashville before heading west across Tennessee to reach Memphis on the Mississippi River. The drive typically takes 5.5 hours. This route connects the Bluegrass region to the home of the blues.

Total Distance: 560 km driving distance; 500 km straight-line air distance.
Fastest Way
Driving is the fastest method, taking approximately 5.5 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective way to travel.
Compare Shepherdsville to Memphis Routes
Driving
Direct
Duration
5 hours 30 mins
Avg Price
$70-$85 in fuel
Operator
Personal Vehicle
Route
I-65 South to I-40 West through Nashville and Jackson, Tennessee.

The stretch between Nashville and Memphis is relatively flat and straightforward.

Travel Tips
  • Traffic
    Avoid driving into Memphis during morning and evening rush hours.
  • Parking
    Downtown Memphis has many parking garages; check rates in advance.
  • Dining
    Try Memphis-style barbecue at local restaurants.
  • Weather
    Memphis can be very hot and humid in the summer; stay hydrated.
  • Rest Stops
    There are many rest areas along I-40 in Tennessee.
Safety Tips
  • Speed Limits
    Tennessee state police are active on I-40; watch your speed.
  • Vehicle Maintenance
    The 5.5-hour drive requires a reliable vehicle; check your tires before leaving.
  • Night Driving
    The stretch near Memphis can be busy; stay alert.
  • Emergency Kit
    Keep a basic emergency kit in your car for the long journey.
People Also Ask
  • Is there a train to Memphis?
    No direct train service exists from Shepherdsville.
  • How long is the drive?
    It takes about 5.5 hours under normal conditions.
  • Are there tolls?
    No, I-40 is toll-free on this route.
  • What is the best time to leave?
    Early morning is best to avoid traffic in Nashville and Memphis.
  • Is Memphis walkable?
    The downtown area is walkable, but you will need a car for other parts of the city.
Quick Info
  • From Shepherdsville, Kentucky, United States
  • To Memphis, Tennessee, United States
  • Modes
Best Time to Travel

Spring or Autumn for the best weather in Memphis.

Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley, a must-see for music fans.
2
Beale Street
Experience the famous street known for its blues clubs and nightlife.
3
National Civil Rights Museum
Learn about the history of the civil rights movement at the Lorraine Motel.
4
Sun Studio
Tour the studio where rock and roll history was made.
Tags
Shepherdsville to Memphis drive I-65 and I-40 route Kentucky to Tennessee travel Memphis road trip driving to Memphis Memphis transport guide fastest way to Memphis traveling south from Kentucky