Is there a train to Memphis?

No direct train service exists from Shepherdsville.

How long is the drive?

It takes about 5.5 hours under normal conditions.

No, I-40 is toll-free on this route.

What is the best time to leave?

Early morning is best to avoid traffic in Nashville and Memphis.

The downtown area is walkable, but you will need a car for other parts of the city.

Shepherdsville

Memphis

Driving

Shepherdsville to Memphis

Updated: 31 May 2026

The drive from Shepherdsville to Memphis is approximately 350 miles, primarily using I-65 South and I-40 West. You will travel through Nashville before heading west across Tennessee to reach Memphis on the Mississippi River. The drive typically takes 5.5 hours. This route connects the Bluegrass region to the home of the blues.

Total Distance: 560 km driving distance; 500 km straight-line air distance.

Fastest Way

Driving is the fastest method, taking approximately 5.5 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to travel.

Compare Shepherdsville to Memphis Routes

Driving

Direct

Duration

5 hours 30 mins

Avg Price

$70-$85 in fuel

Operator

Personal Vehicle

Route

I-65 South to I-40 West through Nashville and Jackson, Tennessee.

The stretch between Nashville and Memphis is relatively flat and straightforward.

Travel Tips

Traffic
Avoid driving into Memphis during morning and evening rush hours.
Parking
Downtown Memphis has many parking garages; check rates in advance.
Dining
Try Memphis-style barbecue at local restaurants.
Weather
Memphis can be very hot and humid in the summer; stay hydrated.
Rest Stops
There are many rest areas along I-40 in Tennessee.

Safety Tips

Speed Limits
Tennessee state police are active on I-40; watch your speed.
Vehicle Maintenance
The 5.5-hour drive requires a reliable vehicle; check your tires before leaving.
Night Driving
The stretch near Memphis can be busy; stay alert.
Emergency Kit
Keep a basic emergency kit in your car for the long journey.