No, there is no direct bus service.

How long is the drive?

The drive takes about 1.25 hours.

No, there is no direct train service.

What is the best route?

US-501 South to I-85 South is the most direct route.

Is it a scenic drive?

Yes, it offers a pleasant view of the Virginia and North Carolina countryside.

South Boston

Durham

Driving

South Boston to Durham

Updated: 28 May 2026

The trip from South Boston, Virginia to Durham, North Carolina is a 70-mile journey across the state line. Driving is the most practical method, taking approximately 1.25 hours via US-501 South and I-85 South. This route takes you from the rolling hills of Virginia into the vibrant city of Durham. There is no direct train or bus service between these two points, making personal vehicle travel the preferred choice. Plan for a quick and easy commute between these two cities.

Total Distance: Driving distance 115 km, straight-line air distance 100 km.

Fastest Way

Driving, 1.25 hours.

Cheapest Way

Driving, as it is the only practical method.

Compare South Boston to Durham Routes

Driving

Direct

Duration

1.25 hours

Avg Price

$15-$25

Operator

Personal Vehicle

Route

US-501 S to I-85 S

I-85 is a major highway; expect some traffic near Durham.

Travel Tips

Traffic
Expect heavier traffic on I-85 during weekday rush hours near Durham.
Navigation
Use a GPS to navigate through Durham's city streets to your final destination.
Parking
Downtown Durham has various parking garages and street parking options.
Fuel
Gas stations are readily available along the route.
Road Conditions
Check for road construction on I-85 before you leave.