Is there a train from St. Louis to Detroit?

No direct Amtrak service exists; you would need to transfer in Chicago.

How long is the drive?

The drive typically takes 7 to 8 hours.

Are there tolls on this route?

Yes, the Ohio Turnpike requires tolls.

What is the best airport in Detroit?

Detroit Metropolitan Airport (DTW) is the primary hub.

Is it better to fly or drive?

Flying is faster, but driving is cheaper for multiple passengers.

St. Louis

Detroit

Flight Driving

St. Louis to Detroit

Updated: 28 May 2026

The journey from St. Louis to Detroit spans approximately 780 kilometers through the heart of the Midwest. Driving via I-70 East and I-75 North takes roughly 7 to 8 hours depending on traffic near Indianapolis. Alternatively, direct flights from St. Louis Lambert International Airport to Detroit Metropolitan Airport take about 90 minutes. This route traverses the industrial corridors of Indiana and Ohio. You will experience a mix of urban landscapes and rolling plains. Planning your departure to avoid rush hour in Indianapolis is essential for a smooth trip.

Total Distance: 780 km driving distance; 650 km straight-line air distance.

Fastest Way

Flying is the fastest method, saving over 5 hours of travel time.

Cheapest Way

Driving is the most cost-effective option for groups or families.

Compare St. Louis to Detroit Routes

	Flight Direct	Driving Direct
Duration	1 hour 45 mins	7 hours 30 mins
Avg Price	$250 - $450	$80 - $120 in fuel
Operator	Delta Air Lines	Personal Vehicle
Route	STL to DTW	I-70 East to I-75 North via Indianapolis and Toledo.
Tip	Book at least three weeks in advance to secure lower fares.	Stop in Indianapolis for a mid-way break at the White River State Park.

Travel Tips

Traffic Alert
Expect heavy congestion on I-75 near the Michigan border during weekday afternoons.
Fuel Stops
Fill up in Indiana where gas prices are typically lower than in Michigan.
Airport Parking
Use off-site parking lots near STL to save on daily rates.
Weather Check
Check for lake-effect snow warnings if traveling during winter months.
Toll Roads
Keep a credit card ready for the Ohio Turnpike section of the drive.

Safety Tips

Road Conditions
Monitor local news for construction updates on I-70.
Emergency Kit
Carry a basic roadside emergency kit including jumper cables and water.
Night Driving
Avoid driving through rural stretches of Ohio at night due to deer activity.
Vehicle Check
Ensure your tire pressure is optimal before starting this long-distance drive.