The drive from Staunton to Louisville is approximately 400 miles. You will take I-64 West, which provides a direct and scenic route through the Appalachian Mountains and into the heart of Kentucky. This is a relatively easy drive that takes you through West Virginia and into the Bluegrass State. It is a popular route for those visiting the Kentucky Derby or exploring the bourbon trail.
Total Distance: 645 km driving distance; 550 km straight-line air distance.
The drive through West Virginia is very scenic but has many curves.
May for the Kentucky Derby or September for pleasant weather.