The trip from Sullivan's Island to Columbia covers 190 kilometers. The most efficient route is taking I-526 West to I-26 West. This highway connects the coast directly to the state capital. The drive typically takes 2 hours under normal traffic conditions. You will pass through rural South Carolina landscapes before reaching the urban center.
Total Distance: 190 km driving distance, 175 km straight-line air distance.
I-26 can be busy near the Columbia interchange; plan accordingly.
Autumn months of October and November for pleasant temperatures.