The drive from Wilmington to Columbia is approximately 210 miles, primarily using I-40 West and I-20 West. This route takes you through the heart of the Carolinas, typically taking about three and a half hours. Columbia is the capital of South Carolina and home to the University of South Carolina. It is a straightforward drive through diverse landscapes.
Total Distance: 340 km driving distance; 300 km straight-line air distance.
I-20 is generally well-maintained and easy to navigate.
Spring and Fall are ideal for visiting the Riverbanks Zoo and Garden.