The trip from Sullivan's Island to Durham covers 410 kilometers. You will take I-26 West to I-95 North, then transition to I-40 West toward Durham. This route connects the South Carolina coast to the North Carolina Research Triangle. The drive typically takes 4 hours. Expect heavy traffic on I-95 during peak travel times.
Total Distance: 410 km driving distance, 370 km straight-line air distance.
I-95 is a major trucking route; stay alert and maintain a safe distance.
Spring and Fall for mild weather during city exploration.