The journey from Sumter to Knoxville covers approximately 450 kilometers. Driving via I-26 West and I-40 West is the most direct route, taking about 4.5 hours. This route takes you through the beautiful Appalachian Mountains. Knoxville is known for its vibrant downtown and proximity to the Great Smoky Mountains.
Total Distance: Driving distance 450 km, straight-line air distance 350 km.
Be prepared for winding roads in the mountains.
Spring or Fall for pleasant weather in Tennessee.