Driving
Wausau to La Crosse
Updated: 28 May 2026
The drive from Wausau to La Crosse covers approximately 200 kilometers, taking you through the scenic Driftless Area of Wisconsin. You will typically head south on US-51 and then west on WI-33 to reach the Mississippi River. The journey takes about 2.5 hours and offers beautiful rolling hills and valley views. There is no direct train service, so driving is the most practical and flexible way to travel. This route is particularly beautiful during the autumn months when the foliage is at its peak.
Total Distance: 200 km driving distance; 180 km straight-line air distance.
Fastest Way
Driving via US-51 and WI-33 is the fastest route, taking 2.5 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective way to travel.
Compare Wausau to La Crosse Routes
Driving
Direct
Duration
2 hours 30 mins
Avg Price
$20-$30 in fuel
Operator
Personal Vehicle
Route
US-51 South to WI-33 West
The roads in the Driftless Area are winding; drive carefully.
Travel Tips
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Winding RoadsThe roads in the Driftless Area are very curvy; take your time and watch for other vehicles.
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Scenic ViewsPlan for extra time to stop at the various overlooks along the way.
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Gas StationsFill up in Wausau or Stevens Point, as gas stations can be sparse in the rural valleys.
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DiningLa Crosse has a vibrant downtown with many local restaurants and breweries.
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WeatherThe river valley can be foggy in the mornings; use your headlights.
Safety Tips
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WildlifeBe alert for deer, especially when driving through the wooded valleys.
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Winter DrivingThe hills can be slippery in winter; ensure your vehicle is prepared for icy conditions.
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Emergency KitCarry a basic emergency kit, as some areas have limited cell service.
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Speed LimitsFollow speed limits strictly, as local law enforcement monitors the winding roads.
People Also Ask
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Is there a train to La Crosse?No, there is no direct passenger rail service from Wausau to La Crosse.
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How long is the drive?The drive takes approximately 2 hours and 30 minutes.
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Are there tolls?No, there are no toll roads on this route.
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What is the best route?Taking US-51 South to WI-33 West is the most direct path.
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Is it safe to drive in winter?Yes, but be cautious on the winding roads and hills.
Quick Info
- From Wausau, Wisconsin, United States
- To La Crosse, Wisconsin, United States
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Modes
Best Time to Travel
September and October for the stunning fall colors in the Driftless Area.
Things to Do in La Crosse
1
Grandad Bluff
A massive bluff overlooking the city and the Mississippi River. It offers one of the best views in the entire state.
2
Riverside Park
Located along the Mississippi River, this park is home to the World's Largest Six-Pack and offers great walking paths.
3
Hixon Forest
A large nature area with miles of hiking and mountain biking trails that offer beautiful views of the surrounding valleys.
4
Mississippi River Cruises
Take a boat tour on the river to experience the beauty of the waterway and learn about the local history.
Tags
Wausau to La Crosse drive
US-51 to WI-33
La Crosse travel guide
Mississippi River road trip
Wausau transport
La Crosse driving time
fastest way to La Crosse
Wisconsin highway travel
