Is there a direct train from Ames to Chicago?

No, you must drive to the nearest Amtrak station in Osceola, Iowa.

How long is the drive from Ames to Chicago?

The drive is approximately 5 hours and 45 minutes.

Are there tolls on the way to Chicago?

Yes, the Illinois tollway system requires payment for most major highways.

What is the best way to get to Chicago from Ames?

Driving is the most flexible and often the fastest way to travel.

Can I take a bus to Chicago?

Yes, commercial bus lines operate routes from Des Moines to Chicago.

Ames

Chicago

Train Driving

Ames to Chicago

Updated: 28 May 2026

The journey from Ames to Chicago covers roughly 340 miles. By car, you will primarily take I-35 South to I-80 East, crossing the Mississippi River into Illinois. The drive typically takes 5.5 to 6 hours depending on traffic near the Chicago suburbs. Alternatively, you can drive to Osceola, Iowa, to catch the Amtrak California Zephyr train into Chicago Union Station. This route is a major transit corridor connecting the heart of the Midwest to the Great Lakes.

Total Distance: 547 km driving distance; 480 km straight-line air distance.

Fastest Way

Driving is the fastest method, taking under 6 hours.

Cheapest Way

Driving is generally the cheapest option if traveling with more than one person.

Compare Ames to Chicago Routes

	Train Connecting	Driving Direct
Duration	7 hours	5 hours 45 minutes
Avg Price	$70-$150	$60-$90 in fuel
Operator	Amtrak	Personal Vehicle
Route	Drive to Osceola Station, then take the California Zephyr to Chicago Union Station.	I-35 South to I-80 East through Des Moines and the Quad Cities.
Tip	Book tickets well in advance as prices increase closer to the departure date.	Expect heavy traffic on I-80/I-90 as you approach Chicago.

Travel Tips

Traffic
Avoid entering Chicago during the morning or evening rush hours to save significant time.
Public Transit
Use the 'L' train system once in Chicago to avoid expensive downtown parking.
Tolls
Be prepared for tolls on the Illinois tollway system; an I-PASS transponder is highly recommended.
Parking
Use apps like SpotHero to find discounted parking garages in the city center.
Amtrak
If taking the train, arrive at the Osceola station at least 30 minutes before departure.

Safety Tips

Urban Awareness
Stay aware of your surroundings in crowded tourist areas and keep valuables secure.
Driving
Be cautious of aggressive driving patterns on the I-80/I-90 corridor near the city.
Weather
Chicago can experience rapid weather changes; pack layers for wind and rain.
Emergency
Keep the number for local roadside assistance saved in your phone for the long drive across Illinois.