The journey from Ankeny to Chicago is a 330-mile trip. You will primarily use I-80 East to reach Chicago. The drive typically takes about 5 hours depending on traffic. It is a very straightforward route that connects the suburban area of Ankeny to the city of Chicago.
Total Distance: 530 km driving distance; 500 km straight-line air distance.
Traffic can be heavy during morning and evening rush hours.
Any time of year, as it is a straightforward drive.