The drive from Bishop to Phoenix is approximately 750 kilometers. You will head south on US-395 before turning east on I-10 through the Mojave Desert and into Arizona. The journey typically takes 8 to 9 hours. Be prepared for desert heat and long, straight stretches of road.
Total Distance: 750 km driving distance; 600 km straight-line air distance.
Stop in Blythe for a quick break.
October to April to avoid the intense summer heat.