The drive from Cordova to Knoxville is a 390-mile trip along I-40 East. It takes about 6 hours of driving time. You will travel through the rolling hills of Tennessee. This is a popular route for those traveling between West and East Tennessee. Be prepared for heavy traffic as you enter the Knoxville metropolitan area.
Total Distance: 627 km driving distance; 580 km straight-line air distance.
The drive is very straightforward; just follow the signs for I-40 East.
Spring and fall, when the weather is mild and pleasant.